Ben made a lot of good suggestions (wouldn't know about the strip clubs though - you'll have to take his word for that
).
Besides velocityweekly.com for events/shows listings, you can also look here:
http://www.whylouisville.com/events.asp
and here:
http://www.louisvillehardcore.com/shows/
EarXtacy has sadly gone downhill in the last few years. No 7" selection to speak of really, some vinyl upstairs but it's slim pickins. Still, a very good selection of cds (but a lot of the local bands are spread out in the genre sections for some dumb reason), and the staff are generally good people. You can also try Underground Sounds for some good vinyl (lots of Jazz, Blues, some obscure things hidden around) and all kinda cds.
If you dig used bookstores, you can't miss out on Twice Told Books, on Bardstown Rd. The gentleman running that place is Harold Maier, and he is good people. Check the drawing of Burroughs on the left wall, and there might be some Hunter S. Thompson items around if you look hard. Great selection of books, and even better conversation. He's big into the Jazz too, so there's some of that vinyl around, and some classical. Nice guy -that place has been a favorite since I was an adolescent.
For bars, you never know what you're going to get from one evening to the next. If you want pool, and a decent Juke, there's the Mag bar at 1398 S. Second St. in Old Louisville. Or Cahoot's on Bardstown Rd., in the old building where Tewligan's used to be. Keep in mind though, people peed on that stage (and Jesus Lizard played there), and where the stage was then is now the Cahoot's kitchen. Still, the food's pretty alright. If you want experimental electronic stuff, Red Lounge is doing some of that. And for down-home and dirty, cheap imports and cheaper PBR (edit: and Falls City, how could I forget it - lots of water, so it's nice and cold), try Seidenfaden's. Coffee, try Old Louisville Coffeehouse downtown - 1489 South Fourth Street Corner of 4th and Hill.
If you want some nature, there's Cherokee Park, and you can go downtown and check out the river and bridges or the big lawn thing or skatepark. There are good galleries downtown and on Bardstown Rd and Frankfort Ave. As well as the Speed Museum on the UofL campus downtown. Here's a few galleries, along with some restaurants:
http://www.galleryhop.org/galleries.html
I could go on, but I'll shut up now. If you need any more info, let me know. There's a good bit of stuff
here, along with some history and current info of the punk/indie/hardcore "scene". Lots of places listed, with locations, including bars and other stuff to do.